Dietary Soy Intake and Breast Cancer Risk

Purpose/Objectives: To conduct a metasynthesis of the literature on human studies of the relationship between dietary soy intake and breast cancer risk.






Data Sources: Publications in English reporting human studies were searched with the terms soy and breast cancer, using databases. Only human studies investigating the relationship of soy intake to breast cancer development in women published from January 1997 through June 2008 were included in the review.


使用Ovid®, PubMed, and EBSCO數據庫,以「大豆soy」和「乳癌breast cancer」名詞搜索英文版的人類研究報告。只有從19971月到20086月發表的,調查研究攝食大豆與婦女罹患乳癌關係的人類研究被納入本文回顧。


Data Synthesis: A total of 364 publications were located; 18 of the studies met the inclusion criteria and 18 additional studies were located through other publications identified in the search. Because four articles reported on the same two studies, a total of 34 studies were included in the review.




Conclusions: The naturally occurring dietary intake of soy food or its components appears safe for women without breast cancer; however, the safety of high supplements of soy or its components is less certain.I




mplications for Nursing: Nurses should become more knowledgeable about soy foods and supplements and include soy intake in dietary assessments. Nurses caring for women at high risk for or with a history of breast cancer should confer with dietitians on current practice recommendations. Women with health issues should avoid initiating high intake of soy dietary supplements until the possible effects are better understood.



[摘譯自Carol A. Enderlin, PhD, RN; Elizabeth Ann Coleman, PhD, RNP; AOCN®, Carol Beth Stewart, BS; Reza Hakkak, PhDDietary Soy Intake and Breast Cancer RiskFrom Oncology Nursing Forum Posted: 11/11/2009; Oncol Nurs Forum. 2009;36(5):531-539. © 2009 Oncology Nursing Society]

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